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As of January 1, 2025, the new Act creates "Donor-conceived Personals and Families of Donor-conceived Persons Protection Act". The act requires:

• An ART agency that, on or after January 1, 2025, collects gametes from a donor or matches a donor with a recipient, or receives gametes from a different ART agency, to collect the donor's identifying information and medical history and make a good-faith effort to maintain current contact information and updates on the donor's medical history by requesting updates from the donor at least once every 3 years;
• Upon request of a DCP who is 18 years of age or older, or less than 18 years of age but legally emancipated, release of identifying and medical information to the DCP or the DCP's legal parent or guardian. An ART agency shall not match or provide gametes from a donor who does not agree to the identity disclosure when a DCP reaches 18 years of age;
• An ART agency to collect and securely maintain any records of the donor's identifying information and medical history. The ART agency shall also regularly request at least once every 3 years that a donor provide updates to the donor's contact information and medical history.
• An ART agency that matches or collects gametes from a donor on or after January 1, 2025, who is unknown to the recipient parent at the time of the donation to provide the donor with information about disclosure of information and obtain a declaration from the donor agreeing to identity disclosure when a DCP reaches 18 years of age;
• An ART agency to make and submit a proposed plan to the department of public health and environment (department) to permanently maintain records of donor identifying information and medical history, the number of families established with each donor's gametes, and genetic screening and testing in the event of dissolution, insolvency, or bankruptcy. In the case of such event, the gamete bank shall inform by mail and email, sent to the last known address, all gamete donors whose gametes were collected, matched, or received, as well as recipient parents who received gametes or embryos from the gamete bank.
• That, once an ART agency has record of or should reasonably know that 25 families have been established using a single donor's gametes in or outside of Colorado, with no limit on the number of children conceived by each of the families, the gamete bank shall not match or provide gametes from a donor to additional families.
• On or before January 1, 2025, the department to develop written materials for intended parents and separate materials for donors. An ART agency is required to ensure that, prior to tissue donation or sale of tissue, each tissue donor and intended recipient receives these written materials. The written materials are not meant to be in lieu of any mental health evaluations.
• That donors be at least 21 years of age at the time of the donation;
• On or after January 1, 2025, an ART agency operating in Colorado or providing donor gametes for use in assisted reproduction in Colorado to obtain a license that is conditioned on compliance with the act and its implementing rules.